Safety of Ventilator System

The GeNOsylMV-1000 delivery system incorporates four components: the primary delivery system, a backup system, the NO gas analyzer and the NO2 gas analyzer.  The GeNOsylMV-1000 injects a constant flow of nitric oxide (NO) gas into the inspiratory limb of the ventilator circuit to deliver a constant concentration of NO to the patient.  It provides continuous integrated monitoring of inspired oxygen, NO and nitrogen dioxide (NO2) concentrations, and a comprehensive alarm system.  Prior to reaching the patient, the gas passes through the cartridge which serves two functions: 1) as a mixing chamber, and 2) to chemically convert to NO any NO2 which may be present, so as to deliver NO with extremely low levels of NO2 impurity.

Clinical Development